Viagra Tablets USA in Pakistan

Viagra Tablets USA in Pakistan

Dosage Forms & Strengths

tablet (Revatio)

• 20mg

tablet (Viagra)

• 25mg
• 50mg
• 100mg

injectable solution (Revatio)

• 10mg/12.5mL

oral suspension (Revatio)

• 10mg/mL (when reconstituted)

Erectile Dysfunction

Viagra only

50 mg PO ~1 hr before sexual activity; however, may be taken anywhere from 30 min to 4 hr before sexual activity

Maximum dosing frequency is once per day

Based on effectiveness and toleration, may increase dose to maximum of 100 mg or decrease to 25 mg

Pulmonary Arterial Hypertension

Revatio only

PO: 5 mg or 20 mg TID; administer 4-6 hr apart

IV: 2.5-mg or 10-mg bolus TID if patient is temporarily unable to take PO

Recommended PO/IV dose not to be exceeded

Adding Revatio to bosentan does not have any beneficial effect on exercise capacity

Dosage Modifications

Hepatic impairment

• Viagra Tablets USA in Pakistan

  • Severe (eg, cirrhosis): Consider initial dose of 25 mg

• Revatio

  • Mild or moderate (Child-Pugh A or B): Clearance reduced, resulting in increases in AUC (84%) and Cmax (47%) compared to age-matched volunteers with no hepatic impairment
  • Severe (Child-Pugh C): Not studied

Renal impairment

• Viagra

  • Mild or moderate (CrCl 30-80 mL/min): No dose adjustment required
  • Severe (CrCl <30 mL/min): Consider initial dose of 25 mg

• Revatio

  • Severe (CrCl <30 mL/min): Clearance was reduced, resulting in about doubling of AUC and Cmax compared to age-matched volunteers with no renal impairment